TABLE 10-2
Composition of Normal Human Red Blood Cell Membranes (Ghosts)*
Component
WT%
Grams/Ghost
( x
1013)
Approximate Number of
Molecules/Ghost
( x
106)
% in Outer Half
of Bilayer
%
in Inner Half
of Bilayer
Proteins and glycoproteins
55
5.7
3.7
Lipids
Phospholipids
28
3.0
250
Sphingomyelin
7.1
0.76
65
80
2 0
Phosphatidylcholine
7.9
0.85
70
75
25
Phosphatidylethanolamine
7.8
0.84
70
2 0
80
Phosphatidylserine
3.8
0.41
35
0
1 0 0
Phosphatidylinositols
0.4
0.04
3
2 0
80
Phosphatidic acid
0.4
0.04
3
Unknown
Unknown
Other
0 . 6
0.06
5
Unknown
Unknown
Cholesterol
13
1.3
195
~50
~50
Glycolipids
3
0.3
1 0
1 0 0
0
Free fatty acids
1
0 . 1
2 0
Unknown
Unknown
1 0 0
10.4
480
*Reproduced with permission from J. B. Stanbury, J. W. Wyngaarden, D. S. Fredrickson, et al., Eds.:
The Metabolic Basis of Inherited Disease,
5th ed. (McGraw-Hill, 1983).
